Enhydra fluctuans Lour. aqueous extract inhibited the growth of calcium phosphate crystals: An in vitro study

Autor: Bornika Chattaraj, Arijit Nandi, Anwesha Das, Arun Baidya, Sourav Mahata, Aritra Chowdhury, Soumya Mitra, Sumon Roy, Subrata Chakraborty, Yadu Nandan Dey
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Food Chemistry Advances, Vol 2, Iss , Pp 100287- (2023)
Druh dokumentu: article
ISSN: 2772-753X
DOI: 10.1016/j.focha.2023.100287
Popis: Enhydra fluctuans Lour. is consumed by various tribes in their ethnomedicinal practices for the treatment of kidney stones and urinary problems. However, no scientific studies were conducted to evaluate its effect on crystal growth. Hence, the present study proposed to investigate the effect of aqueous extract of whole plant of standardized E. fluctuans (AEEF) on the growth of calcium phosphate (brushite) crystals. Attempts were also made to evaluate the effect of in vitro free radical scavenging and antimicrobial activities of AEEF. In vitro studies indicated that AEEF (50, 100, and 200 µg/mL) exhibited an inhibitory role on brushite crystal growth. The average length of the deposited brushite crystals was decreased by citric acid (1molL−1) and AEEF (200, 100, and 50 µg/mL) till day 8. Results showed that AEEF (200 and 100 µg/mL) and citric acid significantly (P
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