Heart rate‐corrected QT interval: A novel diagnostic biomarker for diabetic peripheral neuropathy

Autor:	Ai‐jun Jiang, Heng Gu, Zhan‐rong Feng, Ying Ding, Xiao‐hua Xu, Guo‐ping Yin, Wen‐li Zhang, Zi‐yang Shen, Qian Li
Jazyk:	angličtina
Rok vydání:	2022
Předmět:	Diabetes Diabetic peripheral neuropathy Diagnosis Diseases of the endocrine glands. Clinical endocrinology RC648-665
Zdroj:	Journal of Diabetes Investigation, Vol 13, Iss 5, Pp 850-857 (2022)
Druh dokumentu:	article
ISSN:	2040-1124 2040-1116
DOI:	10.1111/jdi.13738
Popis:	Abstract Aims/Introduction To explore the relationship between heart rate‐corrected QT (QTc) interval and diabetic peripheral neuropathy (DPN), and whether QTc interval has diagnostic utility for DPN beyond nerve conduction velocity. Materials and Methods A total of 965 patients with diabetes, including 473 patients with DPN and 492 patients without DPN, underwent standard 12‐lead electrocardiography and detailed assessments of peripheral neuropathy. Results Patients with DPN had longer QTc intervals than those without. Among participants, from the first to fourth quartile of QTc interval, the proportion of patients with DPN appreciably increased and the nerve conduction velocity obviously decreased (P for trend
Databáze:	Directory of Open Access Journals
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