| Autor: |
Shokatayeva Dina, Savitskaya Irina, Kistaubayeva Aida |
| Jazyk: |
English<br />French |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
BIO Web of Conferences, Vol 40, p 01002 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2117-4458 |
| DOI: |
10.1051/bioconf/20214001002 |
| Popis: |
The biological activity of postbiotic from Bacillus subtilis exometabolites was determined due to protein content - 0.541±13.4 mg/ml, the level of proteases - 7.8±0.3 U/ml and the presence of antimicrobial substances. A biocomposite material was developed by co-aggregation of bacterial cellulose, chitosan and Bacillus exometabolites. Modified BC gel film possesses high antagonistic activity against causative agents of wound infections: Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Staphylococcus epidermidis. The use of the obtained material in treatment of wounds on laboratory animals reduces healing time by an average of 20%. The developed bioactive wound dressings is intended for local application in order to optimize the wound healing process. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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