Poor Sleep Quality and Associated Factors in Patients with Common Variable Immunodeficiency

Autor: Eray Yıldız, Şevket Arslan, Buket Tuğan Yıldız, Deniz Tuncel Berktaş, Fatih Çölkesen, Recep Evcen, Filiz Sadi Aykan, Mehmet Kılınç, Gökhan Aytekin, Adem Aydın
Jazyk: English<br />Turkish
Rok vydání: 2022
Předmět:
Zdroj: Türk Uyku Tıbbı Dergisi, Vol 9, Iss 3, Pp 214-220 (2022)
Druh dokumentu: article
ISSN: 2148-1504
DOI: 10.4274/jtsm.galenos.2022.53315
Popis: Objective:This study aimed to examine the sleep quality of common variable immunodeficiency (CVID) patients and to investigate the relationship between sleep quality and depression, anxiety, fatigue, excessive daytime sleepiness and naturel killer (NK) cell counts.Materials and Methods:The study included 53 patients followed with CVID diagnosis. To determine sleep quality and conditions associated with sleep quality in CVID patients, Pittsburgh sleep quality index (PSQI), fatigue severity scale (FSS), Hamilton depression scale (HAM-D), Hamilton anxiety scale (HAM-A) and Epworth sleepiness scale (ESS) were used.Results:Fatigue was found in 37 (70%) patients, poor sleep quality in 34 (64%), depression in 20 (38%), anxiety in 16 (30%), and excessive daytime sleepiness in 11 (21%) patients. All patients CVID patients received immunoglobulin replacement therapy: Intravenous immunoglobulin (IVIG) in 37 (72%) and subcutaneous immunoglobulin (SCIG) in 16 (28%) patients. The PSQI, HAM-A, HAM-D and FSS scores of the patients receiving IVIG treatment were higher than those of the patients receiving SCIG treatment (all, p
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