| Autor: |
Christoph Rieß, Marvin Darkwah Oppong, Thiemo-Florin Dinger, Jan Rodemerk, Laurèl Rauschenbach, Meltem Gümüs, Benedikt Frank, Philipp Dammann, Karsten Henning Wrede, Ulrich Sure, Ramazan Jabbarli |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
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| Zdroj: |
World Neurosurgery: X, Vol 22, Iss , Pp 100302- (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2590-1397 |
| DOI: |
10.1016/j.wnsx.2024.100302 |
| Popis: |
Background: Baseline values and the change of platelet count (PLT) during disease were reported to be associated with prognosis of patients with cancer and intensive care treatment. We aimed to evaluate the association between PLT with the course and prognosis of aneurysmal subarachnoid hemorrhage (SAH). Methods: Admission (AdmPLT) and the 14-days mean PLT (MeanPLT) values of 763 SAH patients treated between 01/2005 and 06/2016 were recorded and, for further analysis, divided into four categories: 400 × 109/L. Primary endpoints were cerebral infarcts in follow-up computed tomography scans, in-hospital mortality and unfavorable outcome at 6-months follow-up defined as modified Rankin scale>3. Adverse events during SAH were assessed as secondary endpoints. Results: Higher PLT values were independently associated with lower risk of cerebral infarction (MeanPLT: aOR = 0.65 per-PLT-category-increase, p = 0.001), in-hospital mortality (AdmPLT: aOR = 0.64, p = 0.017; MeanPLT: aOR = 0.23, p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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