An atlas of endogenous DNA double-strand breaks arising during human neural cell fate determination

Autor: Roberto Ballarino, Britta A. M. Bouwman, Federico Agostini, Luuk Harbers, Constantin Diekmann, Erik Wernersson, Magda Bienko, Nicola Crosetto
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Scientific Data, Vol 9, Iss 1, Pp 1-19 (2022)
Druh dokumentu: article
ISSN: 2052-4463
DOI: 10.1038/s41597-022-01508-x
Popis: Measurement(s) DNA Double Strand Break • Transcriptome • Whole Genome Sequencing • Chromosome conformation capture assay • Tumor Suppressor p53-Binding Protein 1 Technology Type(s) sBLISS - Genome-wide detection of DNA double-strand breaks by in-suspension breaks labeling in situ and sequencing • RNA-seq of total RNA • copy number variation profiling assay • Hi-C • Immunocytochemistry Factor Type(s) Human Neural Cell Fate Specification Sample Characteristic - Organism Homo sapiens Sample Characteristic - Environment cell culture
Databáze: Directory of Open Access Journals
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