Candida parapsilosis sensu stricto Antifungal Resistance Mechanisms and Associated Epidemiology

Autor: Iacopo Franconi, Cosmeri Rizzato, Noemi Poma, Arianna Tavanti, Antonella Lupetti
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Journal of Fungi, Vol 9, Iss 8, p 798 (2023)
Druh dokumentu: article
ISSN: 2309-608X
DOI: 10.3390/jof9080798
Popis: Fungal diseases cause millions of deaths per year worldwide. Antifungal resistance has become a matter of great concern in public health. In recent years rates of non-albicans species have risen dramatically. Candida parapsilosis is now reported to be the second most frequent species causing candidemia in several countries in Europe, Latin America, South Africa and Asia. Rates of acquired azole resistance are reaching a worrisome threshold from multiple reports as in vitro susceptibility testing is now starting also to explore tolerance and heteroresistance to antifungal compounds. With this review, the authors seek to evaluate known antifungal resistance mechanisms and their worldwide distribution in Candida species infections with a specific focus on C. parapsilosis.
Databáze: Directory of Open Access Journals
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