Exposure of Skin Homografts from Related Living Donors to Radiotherapy and Its Effects on Acute Rejection and Wound Healing in Children with Deep Burns: A Randomized Controlled Trial
| Autor: | Mohammed Ahmed Megahed, Sherief Mohamed El Kashty, Ahmed Tharwat Nassar, Mohamed Aboulfetouh, Mohammed Saad AboShaban |
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| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Indian Journal of Plastic Surgery, Vol 55, Iss 01, Pp 081-086 (2022) |
| Druh dokumentu: | article |
| ISSN: | 0970-0358 1998-376X |
| DOI: | 10.1055/s-0041-1740077 |
| Popis: | Background The ideal skin substitute should be more similar to normal skin function while causing fewer reactions. The purpose of this study was to assess the effect of radiotherapy on minimizing acute rejection and enhancing wound healing in children with deep burns. Patients and Methods A prospective randomized control study included 34 children admitted to the burn unit with deep burns under the age of 12 years. Through the tomotherapy device, a skin homograft from a related living donor was exposed to a local dose of radiotherapy of 500 centigray (cGy). It was immediately used for coverage of the prepared bed after the irradiation was completed. Results The mean values of the laboratory parameters (ESR, CRP, IL-6, and TNF) for all burn patients in the study showed a significant difference, with p |
| Databáze: | Directory of Open Access Journals |
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