The effect of multiple evolutionary selections on synonymous codon usage of genes in the Mycoplasma bovis genome.

Autor: Jian-hua Zhou, Yao-zhong Ding, Ying He, Yue-feng Chu, Ping Zhao, Li-ya Ma, Xin-jun Wang, Xue-rui Li, Yong-sheng Liu
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Zdroj: PLoS ONE, Vol 9, Iss 10, p e108949 (2014)
Druh dokumentu: article
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0108949
Popis: Mycoplasma bovis is a major pathogen causing arthritis, respiratory disease and mastitis in cattle. A better understanding of its genetic features and evolution might represent evidences of surviving host environments. In this study, multiple factors influencing synonymous codon usage patterns in M. bovis (three strains' genomes) were analyzed. The overall nucleotide content of genes in the M. bovis genome is AT-rich. Although the G and C contents at the third codon position of genes in the leading strand differ from those in the lagging strand (p
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