Association between low-density lipoprotein cholesterol levels and all-cause mortality in patients with coronary artery disease: a real-world analysis using data from an international network

Autor: Thiago Luis Scudeler, Leandro Menezes Alves da Costa, Rafael Amorim Belo Nunes, Rafael Otto Schneidewind, Thiago Midlej Brito, Daniel Castanho Genta Pereira, Roger Pereira de Oliveira, Gabriela Chaves Santana, Helio Castello, Marcelo José de Carvalho Cantarelli, Álvaro Avezum Junior
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Druh dokumentu: article
ISSN: 2045-2322
DOI: 10.1038/s41598-024-80578-w
Popis: Abstract The current cholesterol guidelines recommend maintaining low levels of low-density lipoprotein cholesterol (LDL-C) in patients with coronary artery disease (CAD). However, recent studies have suggested that both very low and very high LDL-C levels may be associated with increased mortality in the general population. We utilized data from TriNetX, a global health research network, to investigate the association between LDL-C levels and all-cause mortality in patients with CAD. CAD patients were identified using the International Classification of Diseases, Tenth Revision (ICD-10) diagnosis code and stratified into six LDL-C categories:
Databáze: Directory of Open Access Journals
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