The effectiveness of high-flow nasal cannula during sedated digestive endoscopy: a systematic review and meta-analysis

Autor: Yu-Xin Zhang, Xing-Xiang He, Yu-Ping Chen, Shuai Yang
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: European Journal of Medical Research, Vol 27, Iss 1, Pp 1-11 (2022)
Druh dokumentu: article
ISSN: 2047-783X
DOI: 10.1186/s40001-022-00661-8
Popis: Abstract Background Studies evaluating the role of high-flow nasal cannula (HFNC) in sedated digestive endoscopy have reported conflicting results. This meta-analysis evaluates the effectiveness of HFNC in patients undergoing digestive endoscopy procedures under sedation. Methods PubMed, Medline, EMBASE, Cochrane Central Register of Controlled Trials and Web of Science, were searched from inception to 31 July 2021. Only randomized clinical trials comparing HFNC with standard nasal cannula oxygen (SNC) during sedated digestive endoscopy were included. The incidence of hypoxemia was the primary outcome, and the secondary outcome was the percentage of patients who needed airway interventions. Results Seven studies that enrolled 2998 patients were included. When compared to SNC, HFNC was associated with a significant reduction in hypoxemia incidence (OR 0.24, 95% CI 0.09 to 0.64) and airway intervention requirements (OR 0.15, 95% CI 0.03 to 0.69), with both high heterogeneity (I2 = 81% and 94%). In subgroup analysis, when hypoxemia was defined as pulse oxygen saturation (SpO2)
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