| Autor: |
Md Wahiduzzaman, Yuexing Liu, Tao Huang, Wu Wei, Yixue Li |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Biosafety and Health, Vol 4, Iss 4, Pp 220-227 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
2590-0536 |
| DOI: |
10.1016/j.bsheal.2022.03.001 |
| Popis: |
Cell-cell communication is the basis of physiological processes and cell signals. The disease occurs when the cells do not adequately communicate and the messages are blocked. With ligand-receptor interaction databases and single-cell RNA sequencing (scRNA-seq) databases, we can detect intercellular signaling and reconstruct the cell–cell communications among different cell types. This review summarized the computational approaches for analyzing the cell–cell communication based on scRNA-seq data and discussed its applications in carcinogenesis and COVID-19. We believe that this review will accelerate the scRNA-seq data deciphering and facilitate the cell–cell communication studies for complex physiological processes, such as carcinogenesis and SARS-CoV-2 infection. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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