Neurotrophin receptor tyrosine kinases regulated with near-infrared light

Autor: Anna V. Leopold, Konstantin G. Chernov, Anton A. Shemetov, Vladislav V. Verkhusha
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-019-08988-3
Popis: Optical control over receptor tyrosine kinase (RTK) activity can find application in both basic biology and synthetic biology. Here the authors combine the photosensory module of DrBphP bacterial phytochrome with the Trk family of RTKs to obtain Trks that are reversibly switchable with near-infrared and far-red light.
Databáze: Directory of Open Access Journals