Intravenous Immunoglobulin offers temporary improvement in acquired von Willebrand syndrome due to monoclonal gammopathy: A case report

Autor: Kevin G. Zablonski, Aarthi Rajkumar, Lalitha Nayak
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: eJHaem, Vol 5, Iss 4, Pp 833-837 (2024)
Druh dokumentu: article
ISSN: 2688-6146
DOI: 10.1002/jha2.969
Popis: Abstract Acquired von Willebrand syndrome (AVWS) is a bleeding disorder in which an underlying condition induces a quantitative or qualitative deficiency in the von Willebrand factor. This case demonstrates the rare diagnosis of AVWS due to an Immunoglobulin G monoclonal gammopathy in an elderly woman who presented with significant gastrointestinal bleeding. Originally thought to be type 1 von Willebrand disease, this case provides a cautious example to clinicians that without a detailed history or an understanding of the associated laboratory work‐up, AVWS may be missed with potentially fatal consequences. Fortunately, AVWS was recognized and treated with intravenous immunoglobulin with a resolution of bleeding.
Databáze: Directory of Open Access Journals