Prodromal stage of late-onset psychosis

Autor: V. Pochueva, V. Sheshenin, M. Savina, T. Safarova
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: European Psychiatry, Vol 65, Pp S175-S175 (2022)
Druh dokumentu: article
ISSN: 0924-9338
1778-3585
DOI: 10.1192/j.eurpsy.2022.464
Popis: Introduction Prodromal stage of psychosis may be an aim of prevention first episode psychosis. In late-onset psychosis it’s low described. Objectives The aim of this investigation is to describe prodromal phase of late-onset psychosis and their connection with psychopathology. Methods 74 women with late-onset psychosis (age 64,3±6,7) - late-onset schizophrenia (LOS) (n=49, age 63±8,4), schizoaffective disorder (n=17, age 62,4±6,5), late onset delusion disorder (LoDD) (n=8, age 76,6±4,3) underwent clinical assessment (SOPS, PANSS, HAMD-17), cognitive examination (MMSE, MoCA), structured interviewing on life-time pathology. Spearman’s rho statistics was used. Results LOP patients have low prodromal symptoms according to the SOPS score. In LOS patients middle score of SOPS is 18±8,5, in schizoaffective patients middle score of SOPS is 12,3±6,8, and for LoDD SOPS is 13,4 ±4,6. Prodromal disturbances are represented mainly by fragmentary paranoid ideas, thoughts of unusual content, acoasms and affective fluctuations. In LOS patients SOPS negative subscale correlate with HAMD (r=0,384, p
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