Hematological Characteristics of a Sample of Iraqi Patients with Sickle Cell Anemia and Their Correlation with Age and Gender

Autor: Hassan Dede Meshay, Mohammed Haseeb Khamees, Hussein Abdalzehra Wadaha
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Diyala Journal of Medicine, Vol 22, Iss 1 (2022)
Druh dokumentu: article
ISSN: 2219-9764
2617-8982
Popis: Background: Characterization of hematological parameters in patients with sickle cell anemia can direct treatment goals toward strategies reducing morbidity and mortality rate. Objective: To evaluate the hematological parameters in a subset of Iraqi patients with sickle cell anemia in relation to age and gender. Patients and Methods: This cross-sectional study was included 30 patients with sickle cell anemia who were known to be at a steady clinical state with no vaso-occlusive crises. About 5 ml of venous blood was collected in EDTA tube from each participant. The complete blood count was conducted according to standard protocol. Results: The mean age was 7.93 ±2.43 years and the age range was 4 to 12 years. The study included 17 males and 13 females. 29 (96.7 %) were anemic and there was no significant difference in mean hemoglobin levels between males and females (p = 0.838). Males demonstrated higher frequency of low mean cell volume (MCV) and mean cell hemoglobin (MCH) (64.7% and 58.8%, respectively) than females (7.7% and 7.7%, respectively) with highly significant differences. Conclusion: Some hematological parameters in patients with sickle disease are affected by gender but show no significant correlation to age
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