The human central nervous system discharges carbon dioxide and lactic acid into the cerebrospinal fluid

Autor:	Tetsuya Akaishi, Eiko Onishi, Michiaki Abe, Hiroaki Toyama, Kota Ishizawa, Michio Kumagai, Ryosuke Kubo, Ichiro Nakashima, Masashi Aoki, Masanori Yamauchi, Tadashi Ishii
Jazyk:	angličtina
Rok vydání:	2019
Předmět:	Brain metabolism Carbon dioxide Cerebrospinal fluid Functional role Lactic acid Neurology. Diseases of the nervous system RC346-429
Zdroj:	Fluids and Barriers of the CNS, Vol 16, Iss 1, Pp 1-7 (2019)
Druh dokumentu:	article
ISSN:	2045-8118
DOI:	10.1186/s12987-019-0128-7
Popis:	Abstract Background The central nervous system was previously thought to draw oxygen and nutrition from the arteries and discharge carbon dioxide and other metabolic wastes into the venous system. At present, the functional role of cerebrospinal fluid in brain metabolism is not fully known. Methods In this prospective observational study, we performed gas analysis on venous blood and cerebrospinal fluid simultaneously acquired from 16 consecutive preoperative patients without any known neurological disorders. Results The carbon dioxide partial pressure (pCO2) (p
Databáze:	Directory of Open Access Journals
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