Microwave-assisted synthesis of azepines via nucleophilic aromatic substitution
Autor: | Božinović Nina, Šolaja Bogdan A., Opsenica Igor M. |
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Jazyk: | angličtina |
Rok vydání: | 2016 |
Předmět: | |
Zdroj: | Journal of the Serbian Chemical Society, Vol 81, Iss 11, Pp 1225-1230 (2016) |
Druh dokumentu: | article |
ISSN: | 0352-5139 1820-7421 |
DOI: | 10.2298/JSC160824074B |
Popis: | A novel and efficient route has been developed to afford 5H-dipyridoazepine derivatives from primary amines and 3,3'-(Z)-ethene-1,2-di-ylbis(4-chloropyridine). The procedure based on the double nucleophilic aromatic substitution provides a valuable synthetic tool for the synthesis of dipyridoazepines. The reaction proceeds without catalyst, under microwave irradiation condition. [Projekat Ministarstva nauke Republike Srbije, br. 172008] |
Databáze: | Directory of Open Access Journals |
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