The V617F mutation of JAK2 is very uncommon in patients with thrombosis

Autor: Angel F. Remacha, Camino Estivill, M. Pilar Sarda, José Mateo, Joan Carles Souto, Carme Canals, Josep Nomdedéu, Jordi Fontcuberta
Jazyk: angličtina
Rok vydání: 2007
Předmět:
Zdroj: Haematologica, Vol 92, Iss 2 (2007)
Druh dokumentu: article
ISSN: 0390-6078
1592-8721
DOI: 10.3324/haematol.10358
Popis: Given that many cases of thrombosis do not have a clear cause, a myeloproliferative disease could be involved. We investigated the V617F mutation of the JAK2 gene in 295 patients with thrombosis. Only one case was positive. Therefore, the study of this mutation is not necessary in all patients with idiopathic thrombosis.
Databáze: Directory of Open Access Journals