Silencing XIST mitigated lipopolysaccharide (LPS)-induced inflammatory injury in human lung fibroblast WI-38 cells through modulating miR-30b-5p/CCL16 axis and TLR4/NF-κB signaling pathway

Autor: Xu Jiahui, Li Honggui, Lv Ying, Zhang Chang, Chen Yiting, Yu Dezhao
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Open Life Sciences, Vol 16, Iss 1, Pp 108-127 (2021)
Druh dokumentu: article
ISSN: 2391-5412
DOI: 10.1515/biol-2021-0005
Popis: Emerging evidence shows that long noncoding RNA (lncRNA) has been a novel insight in various diseases, including pneumonia. Even though lncRNA X-inactive-specific transcript (XIST) is well studied, its role in pneumonia remains to be largely unrevealed.
Databáze: Directory of Open Access Journals