The Reciprocal Interactions between Polyphenols and Gut Microbiota and Effects on Bioaccessibility

Autor: Tugba Ozdal, David A. Sela, Jianbo Xiao, Dilek Boyacioglu, Fang Chen, Esra Capanoglu
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Nutrients, Vol 8, Iss 2, p 78 (2016)
Druh dokumentu: article
ISSN: 2072-6643
DOI: 10.3390/nu8020078
Popis: As of late, polyphenols have increasingly interested the scientific community due to their proposed health benefits. Much of this attention has focused on their bioavailability. Polyphenol–gut microbiota interactions should be considered to understand their biological functions. The dichotomy between the biotransformation of polyphenols into their metabolites by gut microbiota and the modulation of gut microbiota composition by polyphenols contributes to positive health outcomes. Although there are many studies on the in vivo bioavailability of polyphenols, the mutual relationship between polyphenols and gut microbiota is not fully understood. This review focuses on the biotransformation of polyphenols by gut microbiota, modulation of gut microbiota by polyphenols, and the effects of these two-way mutual interactions on polyphenol bioavailability, and ultimately, human health.
Databáze: Directory of Open Access Journals