Disseminated intravascular coagulation syndrome as a complication in acute spontaneous canine babesiosis

Autor: Oksana A. Dubova, Diana V. Feshchenko, Tetiana I. Bakhur, Oksana A. Zghozinska, Anatoliy A. Antipov, Serhii V. Rublenko, Volodymyr P. Goncharenko, Raisa V. Shahanenko, Volodymyr S. Shahanenko
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Macedonian Veterinary Review, Vol 43, Iss 2, Pp 141-149 (2020)
Druh dokumentu: article
ISSN: 1409-7621
1857-7415
DOI: 10.2478/macvetrev-2020-0027
Popis: The polyetiological syndrome of disseminated intravascular coagulation (DIC) is characterized by changes in patients’ hemostasis. The aim of the current research was to elucidate the main factors for the development of DIC syndrome during canine babesiosis, and to assess their correlation level. Dogs included in this study were of various breeds and sex, weighing 10-40 kg and aged 2-7 years. They were separated in two groups (n=50) according to their diagnosis to babesiosis. Oscillometry (blood pressure, pulse rate), vascular-platelet hemostasis, coagulogram, hematological, biochemical (fibrinogen, fibrin degradation product, soluble fibrin-monomer complex) and hemodynamic (circulating blood volume) assessment methods were used. The group of dogs positive on Babesia spp., had clear manifestation of DIC with 5-7% of the erythrocyte population being affected. DIC was manifested by a significant increase in soluble fibrin-monomer complex and fibrin degradation product (p
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