Case Report: Spontaneous perforation of a bicornuate uterus with concomitant sarcoma [version 2; peer review: 2 approved]

Autor: Soobin Yim, Inji Yeo, Myunghwa Lee, Kyu-Sang Kyeong, Hye-yon Cho, Jung Bae Kang, Min Sun Kyung
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: F1000Research, Vol 9 (2020)
Druh dokumentu: article
ISSN: 2046-1402
DOI: 10.12688/f1000research.25961.2
Popis: A 47-year-old nulliparous, virginal woman presented to the emergency department with acute abdominal pain. Emergency pelvic ultrasound and abdominal CT were taken, which showed a significant amount of hemoperitoneum and a bicornuate uterus with about 18cm x 10cm mass on left uterus. Since the mass had increased vascularity and irregular margins, we thought that the mass could be a uterine sarcoma. MRI and PET/CT were taken additionally for oncologic evaluation before surgery. Intra operative findings showed a ruptured bicornuate uterus with a large mass within the left uterine horn. Total abdominal hysterectomy with bilateral salpingo-oophorectomy was performed. Pathologic analysis confirmed an undifferentiated uterine sarcoma. She was treated with 6 cycles of chemotherapy(etoposide, ifosfamide, cisplatin) postoperatively. Chest and abdomen CT for follow up after chemotherapy showed no sign of cancer recurrence. We suggest a bicornuate uterus with concomitant sarcoma should be concerned as a possible cause of uterine rupture by reviewing this case.
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