| Autor: |
I. A. Pirozhkov, M. E. Malyshev, O. N. Reznik, V. A. Manukovsky, A. E. Skvortsov |
| Jazyk: |
ruština |
| Rok vydání: |
2018 |
| Předmět: |
|
| Zdroj: |
Вестник трансплантологии и искусственных органов, Vol 20, Iss 3, Pp 87-94 (2018) |
| Druh dokumentu: |
article |
| ISSN: |
1995-1191 |
| DOI: |
10.15825/1995-1191-2018-3-87-94 |
| Popis: |
Allogeneic kidney transplantation is the optimal approach for the treatment of patients with terminal stage of chronic kidney disease. Moreover, post-transplant monitoring and optimization of immunosuppressive therapy with early non-invasive molecular-biological markers can significantly improve the long-term outcome of transplantation. As markers of damage to the kidney transplant, it is proposed to use micro-RNAs that play a fundamental role in the regulation of the activity of various genes. The level of expression of micro-RNA in different tissues can correlate with certain pathological conditions. In this review, the literature data on the study of the perspectives for the use of micro-RNA as biomarkers of the post-transplantation period in kidney transplant recipients are considered. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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