Postnatal Development of Endocrine Pancreatic Islets of an Egyptian One-humped Camel (Camelus dromedarius)

Autor: Ahmed Mohamed Rashwan
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: SVU-International Journal of Veterinary Sciences, Vol 6, Iss 1, Pp 152-165 (2023)
Druh dokumentu: article
ISSN: 2535-1826
2535-1877
DOI: 10.21608/SVU.2023.179071.1242
Popis: This study aimed to ascertain the morphological and morphometric development of pancreatic islets as well as the average levels of numerous hormones during the postnatal development of camel pancreatic islets. Until recently, there has been no information on the aging development of pancreatic islets in the camel pancreas. In this study, three different ages (4 years, 8 years, and 18 years) were examined using histochemistry. The diameter of the camel pancreatic islet increased from 70.3 ± 1.5 µm in 4 years to 97 ± 1.6 µm in 18 years. The insulin cells were distributed all over the pancreatic islets, and their average increased from 65.7% in 4 years to 77.6% in 18-year-old camels. The glucagon cells were distributed in the periphery, and their percentage was around 11.2% in 4 years and 14.8% in 18 years. The somatostatin cells were distributed throughout the islets; their percentage was around 7.5% in 4 years and 9.4% in 18 years. This study examined the proliferation of pancreatic islets in order to comprehend the process that increases the size of pancreatic islets and insulin cells. There is no prior information describing the proliferation of beta cells in camel pancreatic islets. The proliferation was around 5.4% in insulin cells at 4 years and increased to 7.8% in insulin cells at 8 years. The current research clarifies that the size of pancreatic islets increases, and the percentage of insulin cells rise with aging, which is essential for maintaining blood glucose levels and aids camels in longterm adaptation to famine.
Databáze: Directory of Open Access Journals