The Protective Role of Poplar Propolis Against Alcohol-Induced Biochemical and Histological Changes in Liver and Testes Tissues of Rats

Autor: Numan Baydilli, Emre Can Akınsal, Züleyha Doğanyiğit, Oğuz Ekmekçioğlu, Sibel Silici
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Erciyes Medical Journal, Vol 42, Iss 2, Pp 132-138 (2020)
Druh dokumentu: article
ISSN: 2149-2247
DOI: 10.14744/etd.2020.83097
Popis: Objective: This study evaluated the biochemical and histopathological effects of propolis oil extract on liver and testicular tissue in rats subjected to alcohol toxicity. Materials and Methods: Sixty Wistar albino rats were randomly assigned into 6 groups: Control, Ethanol (EtOH: 20% ethanol) Propolis-1 (PR1: 100 mg/kgbw) Propolis-2 (PR2: 200 mg/kgbw) EtOH+PR1, and EtOH+PR2. Rats were administered ethanol and propolis by gastric tube for 15 days. Hematological, biochemical, and histopathological (liver and testes) parameters were examined. In addition, sperm concentration and motility were determined. Results: Increased deterioration of complete blood count parameters was statistically significant in the EtOH group when compared to the control group. Propolis was preventative for some effects of EtOH. The most pronounced preventive effect of propolis on ethanol-induced damage was observed in nucleated red blood cells (NRBC) and mean corpuscular hemoglobin concentration (MCHC) parameters (p
Databáze: Directory of Open Access Journals