Olanzapine-induced multifactorial chylomicronaemia syndrome: a rare but important complication

Autor: Bridget Cooper, Kenrick Blaker, Jerry R Greenfield
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Endocrinology, Diabetes & Metabolism Case Reports, Vol 1, Iss 1, Pp 1-4 (2023)
Druh dokumentu: article
ISSN: 2052-0573
DOI: 10.1530/EDM-22-0225
Popis: We present a case of a 42-year-old man who developed acute onset severe hypertriglyceridaemia within days of commencing olanzapine therapy. Despite having a family history of metabolic syndrome, he had no personal history of hyperlipidaemia and had normal fasting lipids 1 week prior to treatment initiation. His case is consistent with a diagnosis of multifactorial chylomicronaemia syndrome with a possible undiagnosed underlying genetic lipid metabolism disorder. Our case highlights the difficulty in identifying patients at risk of severe hypertriglyceridaemia prior to the commencement of olanzapine.
Databáze: Directory of Open Access Journals