| Autor: |
Zehra Banu Bahsi Oral |
| Jazyk: |
English<br />Turkish |
| Rok vydání: |
2019 |
| Předmět: |
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| Zdroj: |
Düzce Üniversitesi Bilim ve Teknoloji Dergisi, Vol 7, Iss 3, Pp 1806-1812 (2019) |
| Druh dokumentu: |
article |
| ISSN: |
2148-2446 |
| DOI: |
10.29130/dubited.558155 |
| Popis: |
Alkanethiol self-assembled monolayers (SAMs) with Peptide Nucleic Acid (PNA) were proposed as a novel probe design in electrochemical biosensors. This paper investigates the optimization of PNA probe by using two different concentrations of SAMs, immobilization temperature, and two-stage immobilization process. Alkanethiol self-assembled monolayers with PNA probe immobilization and cDNA (complementary DNA) hybridization were measured via AC voltammetry method. The small negative shift in formal potential (-17 mV) was occurred after cDNA hybridization at high ionic strength concentration. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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