INVESTIGATION OF NEUROPROTECTIVE ACTIVITY THIOPHANE INVOLUTIONAL CHORIORETINAL DEGENERATION IN RATS OXYS

Autor:	A. A. Zhdankina, G. A. Kon, M. B. Plotnikov, Ye. Yu. Varakuta, S. V. Logvinov, A. Ye. Prosenko, N. G. Kolosova
Jazyk:	English<br />Russian
Rok vydání:	2013
Předmět:	морфология сетчатки центральная хориоретинальная дегенерация крысы oxys антиоксидантная активность свободные радикалы люминол-зависимая хемилюминесценция тиофан Medicine
Zdroj:	Бюллетень сибирской медицины, Vol 12, Iss 3, Pp 24-32 (2013)
Druh dokumentu:	article
ISSN:	1682-0363 1819-3684 45641560
DOI:	10.20538/1682-0363-2013-3-24-32
Popis:	The method of spontaneous and induced luminol -dependent chemiluminescence in homogenates of rat retinas OXYS registered increase in the generation of free radicals against decrease in total antioxidant activity. With the ultra-microscopic and quantitative analysis revealed degenerative retinal neurons rats OXYS: the percentage increase in neurosensory cells with pyknosis of nuclei, hyperchromatic piknomorfnyh associative neurons and ganglion n eurons that have been modified on a light and dark type. Thiophane, limiting free radical reactions in the retina and protects retinal neurons from damage.
Databáze:	Directory of Open Access Journals
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