| Autor: |
Jianchuan Wang, Yang Su, Roxana E. Iacob, John R. Engen, Timothy A. Springer |
| Jazyk: |
angličtina |
| Rok vydání: |
2019 |
| Předmět: |
|
| Zdroj: |
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019) |
| Druh dokumentu: |
article |
| ISSN: |
2041-1723 |
| DOI: |
10.1038/s41467-019-13248-5 |
| Popis: |
The activation mechanism of integrin αVβ8 differs from other integrins. Combining X-ray crystallography, hydrogen deuterium exchange mass spectrometry and mutation, the authors reveal structural features responsible for these differences and provide insights into how typical integrins are regulated. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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