New formulation calcium-based 45S5 bioactive glass: In vitro assessment in PBS solution for potential dental applications

Autor: Zhi Wei Loh, Mohd Hafiz Mohd Zaid, Mohd Mustafa Awang Kechik, Yap Wing Fen, Khamirul Matori Amin, Wei Mun Cheong
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Journal of Materials Research and Technology, Vol 24, Iss , Pp 3815-3825 (2023)
Druh dokumentu: article
ISSN: 2238-7854
DOI: 10.1016/j.jmrt.2023.04.071
Popis: In this work, the designed bioactive glass utilized waste is expected to improve mechanical properties while maintaining the bioactivity performance during the in-vitro assessment. Herein, the novel bioactive glasses were prepared using the melt-quenching approach. Phosphate buffer saline was used as an immersion medium during the in-vitro bioactivity and biodegradability evaluation to ascertain the glass's bioactivity characteristics. The XRD results indicated the carbonate apatite phase for sample 0F and the fluorapatite and calcite phase for sample 3F, supported by the FTIR spectra. Further, the pH increased from (7.437 ± 0.004) to (9.699 ± 0.058) for 0F and (9.635 ± 0.014) for 3F, indicating the samples' bioactivity in response to the immersion medium. In addition, 3F exhibited a higher hardness (3.29 ± 0.07 GPa) and toughness (2.4 ± 0.08 MPa m1/2), supported by the weight gained in the biodegradability analysis. This work offers a promising technique to fabricate the bioactive glass incorporating waste, adding fluoride content into the glass for potential dental application.
Databáze: Directory of Open Access Journals