Tissue-resident memory T cells play a key role in the efficacy of cancer vaccines

Autor:	C. Granier, C. Blanc, S. Karaki, T. Tran, H. Roussel, E. Tartour
Jazyk:	angličtina
Rok vydání:	2017
Předmět:	resident memory t cell cancer vaccine tumor microenvironment route of immunization immunosurveillance Immunologic diseases. Allergy RC581-607 Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Zdroj:	OncoImmunology, Vol 6, Iss 11 (2017)
Druh dokumentu:	article
ISSN:	2162-402X 2162402X
DOI:	10.1080/2162402X.2017.1358841
Popis:	Resident memory CD8+T cells (TRM) usually defined by the CD103 marker represent a new subset of long-lived memory T cells that remain in the tissues. We directly demonstrate their specific role in cancer vaccine-induced tumor regression. In human, they also seem to play a major role in tumor immunosurveillance.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/438097838eae48c6b0bd07f878f6c4da Zobrazit plný text záznamu View record in DOAJ