Impact of phase angle and sarcopenia estimated by bioimpedance analysis on clinical prognosis in patients undergoing hemodialysis

Autor: Eunjin Bae, MD, PhD, Tae Won Lee, MD, Wooram Bae, MD, Seongmin Kim, MD, Jungyoon Choi, MD, Ha Nee Jang, MD, Se-Ho Chang, MD, PhD, Dong Jun Park, MD, PhD
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Medicine, Vol 101, Iss 25, p e29375 (2022)
Druh dokumentu: article
ISSN: 0025-7974
1536-5964
00000000
DOI: 10.1097/MD.0000000000029375
Popis: Abstract. Bioimpedance analysis (BIA) has been widely used in the evaluation of body composition in patients undergoing maintenance hemodialysis. We conducted this study to evaluate impact of phase angle (PA) and sarcopenia measured by BIA on clinical prognosis in these patients. This longitudinal retrospective study enrolled patients who underwent hemodialysis between January 2016 and March 2019. The patients were stratified into higher (> 4°) and lower (≤ 4.0°) PA groups. Sarcopenia was defined when the appendicular skeletal muscle mass was < 20 kg in men and < 15 kg in women. Of the 191 patients, 63.4% were men. The mean age was 64.2 ± 12.4 years. The lower PA group was older, had a higher proportion of women, a lower body mass index, lower albumin, cholesterol, uric acid, and phosphorus levels, and a higher incidence of history of coronary artery disease than the higher PA group. Linear regression analysis revealed that PA was significantly associated with body mass index (B = 0.18, P = .005), serum albumin (B = 0.23, P = .001), and creatinine levels (B = 0.32, P
Databáze: Directory of Open Access Journals