烟雾血管病与免疫相关疾病 Moyamoya Angiopathy and Immune-Related Diseases

Autor: 汪敏杰1,2,韩聪1,2,段炼1,2 (WANG Minjie1,2, HAN Cong1,2, DUAN Lian1,2 )
Jazyk: čínština
Rok vydání: 2024
Předmět:
Zdroj: Zhongguo cuzhong zazhi, Vol 19, Iss 7, Pp 747-754 (2024)
Druh dokumentu: article
ISSN: 1673-5765
DOI: 10.3969/j.issn.1673-5765.2024.07.003
Popis: 烟雾血管病是一类病因不明的颅内大动脉闭塞性疾病,主要表现为颈内动脉系统慢性狭窄、闭塞和异常血管网的形成。临床和流行病学研究发现,烟雾血管病患者具有较高的免疫相关疾病患病率,提示免疫因素在烟雾血管病的发生、发展中扮演了重要角色。本文旨在对烟雾血管病与感染、血管炎及自身免疫性疾病等免疫相关疾病的相关性研究展开综述,探讨免疫相关疾病参与烟雾血管病发病的潜在机制。 Abstract: Moyamoya angiopathy (MMA) is an intracranial large artery occlusive disease of unknown etiology, characterized by chronic stenosis/occlusion of the internal carotid artery system and the formation of abnormal vascular networks. Clinical and epidemiological studies have demonstrated that patients with MMA have a higher prevalence of immune-related diseases, suggesting that immune factors play an important role in the occurrence and progression of MMA. This paper aims to review the correlation between MMA and immune-related diseases such as infections, vasculitis, and autoimmune diseases, and explore the potential mechanisms of immune-related diseases involved in the pathogenesis of MMA.
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