Programming mRNA decay to modulate synthetic circuit resource allocation

Autor: Ophelia S. Venturelli, Mika Tei, Stefan Bauer, Leanne Jade G. Chan, Christopher J. Petzold, Adam P Arkin
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/ncomms15128
Popis: Synthetic circuits in host cells compete with endogenous processes for limited resources. Here the authors use MazF to funnel cellular resources to a synthetic circuit to increase product production and demonstrate how resource allocation can be manipulated.
Databáze: Directory of Open Access Journals