Mother‐child cardiometabolic health 4–10 years after pregnancy complicated by obesity with and without gestational diabetes

Autor: Samantha L. Martin, Li Zhang, Makenzie L. Callahan, Jessica Bahorski, Cora E. Lewis, Bertha A. Hidalgo, Nefertiti Durant, Lorie M. Harper, Ashley N. Battarbee, Kirk Habegger, Bethany A. Moore, Alysha Everett, Stella Aslibekyan, Rogerio Sertie, Nengjun Yi, W. Timothy Garvey, Paula Chandler‐Laney
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Obesity Science & Practice, Vol 8, Iss 5, Pp 627-640 (2022)
Druh dokumentu: article
ISSN: 2055-2238
DOI: 10.1002/osp4.599
Popis: Abstract Objective Obesity in pregnancy and gestational diabetes (GDM) increase cardiometabolic disease risk but are difficult to disentangle. This study aimed to test the hypothesis that 4–10 years after a pregnancy complicated by overweight/obesity and GDM (OB‐GDM), women and children would have greater adiposity and poorer cardiometabolic health than those with overweight/obesity (OB) or normal weight (NW) and no GDM during the index pregnancy. Methods In this cross‐sectional study, mother‐child dyads were stratified into three groups based on maternal health status during pregnancy (OB‐GDM = 67; OB = 76; NW = 76). Weight, height, waist and hip circumferences, and blood pressure were measured, along with fasting glucose, insulin, HbA1c, lipids, adipokines, and cytokines. Results Women in the OB and OB‐GDM groups had greater current adiposity and poorer cardiometabolic health outcomes than those in the NW group (p
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