Langerhans cell histiocytosis presenting as eosinophilic granuloma of the bilateral forearms in an 8-year-old girl: a case report

Autor: Salahoudine Idrissa, Hind Cherrabi, Boubacar Efared, Kassim Sidibé, Karima Attaraf, Lamiae Chater, Abderahmane Afifi
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Journal of Medical Case Reports, Vol 13, Iss 1, Pp 1-4 (2019)
Druh dokumentu: article
ISSN: 1752-1947
DOI: 10.1186/s13256-019-2011-1
Popis: Abstract Background Langerhans cell histiocytosis previously known as histiocytosis X is a rare disease of children and young adults with a very broad clinical spectrum. In children, its annual incidence is estimated between 0.2–0.5 per 100,000. Case representation An 8-year-old Moroccan girl with no known personal or family history presented to our institution with painful swelling of both forearms. An X-ray and magnetic resonance imaging were inconclusive. We then performed a biopsy curettage (of her left forearm). Microscopic analysis followed by immunohistochemical analysis disclosed a diagnosis of Langerhans cell histiocytosis. No chemotherapy was necessary. Clinical and radiological improvement was achieved after 6 months. Conclusion The particularity of this observation is the bilaterality of the lesion on both forearms and it has not previously been reported. Langerhans cell histiocytosis should be included in the differential diagnosis of osteomyelitis and Ewing’s sarcoma.
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