Relationship between HbA1c and continuous glucose monitoring in Chinese population: a multicenter study.

Autor: Jian Zhou, Yifei Mo, Hong Li, Xingwu Ran, Wenying Yang, Qiang Li, Yongde Peng, Yanbing Li, Xin Gao, Xiaojun Luan, Weiqing Wang, Yun Xie, Weiping Jia
Jazyk: angličtina
Rok vydání: 2013
Předmět:
Zdroj: PLoS ONE, Vol 8, Iss 12, p e83827 (2013)
Druh dokumentu: article
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0083827
Popis: OBJECTIVE: Since there is a paucity of reference data in the literature to indicate the relationship between HbA1c, and 24 h mean blood glucose (MBG) from continuous glucose monitoring (CGM) in Chinese populations, we described the above relationship in adult Chinese subjects with different glucose tolerance status. METHODS: Seven-hundred-and-forty-two individuals without history of diabetes were included to the study at 11 hospitals in urban areas across China from 2007-2009 and data of 673 subjects were included into the final analysis. Oral glucose tolerance test (OGTT) classified the participants as nondiabetic subjects, including those with normal glucose regulation (NGR; n = 121) and impaired glucose regulation (IGR; n = 209), or newly diagnosed type 2 diabetes (n = 343). All participants completed testing for HbA1c levels and wore a CGM system for three consecutive days. The 24 h MBG levels were calculated. Spearman correlations and linear regression analyses were applied to quantify the relationship between glucose markers. RESULTS: The levels of HbA1c and 24 h MBG significantly increased with presence of glucose intolerance (NGR
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