The genetic analysis of broiler-origin h9n2 influenza virus with internal genes highly homologous to the recent human h3n8 virus

Autor: Peidong LI, Jinbo YANG, Hao ZHU, Xue WANG, Hao SHI, Shiqiang CHENG, Li MA, Tianyao YANG, Sheng ZHOU, Zhaoyang LI, Chunguo LIU
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Kafkas Universitesi Veteriner Fakültesi Dergisi, Vol 29, Iss 2, Pp 201-206 (2023)
Druh dokumentu: article
ISSN: 1309-2251
DOI: 10.9775/kvfd.2022.28820
Popis: The most prevalent subtype of avian influenza worldwide, H9N2, not only threatens human health and causes enormous financial losses in the poultry sector but also has the potential to be transmitted directly or indirectly between other species. This study discovered four H9 subtype avian influenza virus in Fujian in 2022. According to genetic analysis, these four viruses contain several binding sites for mammalian receptors (216 L and 217 M in HA gene). More crucially, the internal genes of the two isolates of XD-L2 and XD-L4 were closely related to those of the human H3N8 virus found this year, which could pose a threat to human health, especially that of poultry producers.
Databáze: Directory of Open Access Journals