| Autor: |
Christian Ejike Onah, Chinwemma Florence Onah, Stephen Monday Suru, Chinedu Michael Olisah, Alfred Friday Ehiaghe, Chukwuemeka Emmanuel Ogbodo, Wuraola Serah Nnaemeka, Ukamaka Ann Ijeomah, Chukwuemeka Samuel Meludu, Chudi Emmanuel Dioka |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
Avicenna Journal of Medical Biochemistry, Vol 11, Iss 1, Pp 41-45 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2345-4113 |
| DOI: |
10.34172/ajmb.2023.2430 |
| Popis: |
Background: Lead is a highly toxic metal of great public health importance. Objectives: This cross-sectional study was conducted to evaluate the kidney and liver function status and the markers of oxidative stress among lead recycling factory workers in Anambra State, Nigeria. Methods: A total of 82 subjects (41 experimental and 41 control subjects) aged 20-60 years were recruited in this study. Lead levels in whole blood were measured using atomic absorption spectrometry. Serum malondialdehyde (MDA) and uric acid levels as well as the activities of glutathione S-transferase (GST), alanine transaminase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), and γ-glutamyltransferase (γ-GT) were measured using the spectrophotometric method. Superoxide dismutase (SOD) and catalase activities were determined using colorimetric method and Berthelot’s and Jaffe slot methods were used to measure urea and creatinine levels, respectively. Results: The mean activities of SOD, GST, and catalase as well as estimated glomerular filtration rate (eGFR) were significantly lower in lead recycling workers compared with control group (P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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