| Autor: |
M.C.P. Gouveia, B.W. Minto, L.F. Sargi, R.L. Souza, J.M. Pazzini, E.M. Colodel, V.C.P. Silva, P.C. Cassino, L.G.G.G. Dias |
| Jazyk: |
English<br />Portuguese |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Arquivo Brasileiro de Medicina Veterinária e Zootecnia, Vol 73, Iss 6, Pp 1315-1322 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
1678-4162 |
| DOI: |
10.1590/1678-4162-12289 |
| Popis: |
ABSTRACT The aim of this study was to evaluate the topical application of alcoholic extracts of Dipteryx alata Vogel almonds and bark in skin wound healing in mice. Fifty-four C57BL/6 mice were equally distributed into three groups: Control, Almond, and Bark. A 9 mm skin fragment was resected from the dorsal region of the animals’ thorax. The wounds were submitted to topical application of base cream (vehicle), 10% hydroalcoholic almond extract, or bark extract twice a day. Macroscopic, histological, and immunohistochemical evaluations were conducted on the 7th, 14th, and 21st postoperative days. No significant difference was observed regarding skin wound area among groups, with the parameter presenting only a temporal effect on healing (p>0.05). The almond and control groups exhibited more intense collagenization than the bark group (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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