The role of tamoxifen in the therapy of metastatic ovarian cancer

Autor: I S Davidenko, M V Kazantseva, N V Porhanova, M R Ohanyan
Jazyk: ruština
Rok vydání: 2014
Předmět:
Zdroj: Современная онкология, Vol 16, Iss 1, Pp 26-29 (2014)
Druh dokumentu: article
ISSN: 1815-1434
1815-1442
Popis: Ovarian cancer is one of the most widely spread among women malignant tumors. Despite high sensitivity to anti-cancer chemotherapy (responses are awaited from more than 80% of women, receiving standard therapy with platinum and paclitaxel) recurrence of the disease takes place and the tumor becomes resistant to further therapy. Thus, it becomes necessary to invent new types of non-toxic therapy, taking into consideration biological qualities of the tumor. Tamoxifen therapy has efficacy in previously intensively treated patients with metastatic ovarian cancer, and it has low toxicity as well.
Databáze: Directory of Open Access Journals