| Autor: |
Maria Camila Pérez, Jaime Fernández-Sarmiento, Juan David Bustos, Sarah Ferro-Jackaman, Paula Ramírez-Caicedo, Andrés Nieto, Natalia Lucena, Sofia Barrera, José Manuel Fernández-Rengifo, Carolina Cárdenas, Maria Camila Garavito, Juan Pablo Fernández-Sarta, Isabella La Rotta, Alejandro Coutin, Juanita Patiño, Lorena Acevedo, Juan David Suárez, Catalina Duque-Arango |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
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| Zdroj: |
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2045-2322 |
| DOI: |
10.1038/s41598-024-73112-5 |
| Popis: |
Abstract A lactate/albumin ratio (LAR) greater than 0.5 measured early in the course of pediatric critical illness is associated with greater mortality. Whether the elevated LAR can be explained by microcirculation disorders in children with sepsis is not known. In this longitudinal retrospective study (January 2021-January 2024), serum albumin and lactate were measured on admission to the pediatric intensive care unit (PICU), with sublingual video microscopy performed simultaneously to measure microcirculation. A total of 178 children were included, 37% of whom had septic shock measured with the Phoenix Sepsis Score. Patients with remote sepsis had greater odds of an elevated LAR (aOR 6.87: 95% CI 1.98–23.73; p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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