Anti-Gastric Ulcer Activity of the Water Extract from Payawanorn (Pseuderanthemum Palatiferum)
| Autor: | Kannika Inchab, Parirat Khonsung, Natthakarn Chiranthanut, Puongtip Kunanusorn, Saranyapin Potikanond, Sunee Chansakaow, Ampai Panthong, Seewaboon Sireeratawong |
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| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: | |
| Zdroj: | Journal of Health Science and Medical Research (JHSMR), Vol 36, Iss 2, Pp 89-95 (2018) |
| Druh dokumentu: | article |
| ISSN: | 2586-9981 2630-0559 |
| DOI: | 10.31584/jhsmr.2018.36.2.1 |
| Popis: | Objective: To examine the anti-gastric ulcer activity of Payawanorn (Psuderanthemum palatiferum) water extract (PPE) in rats.Material and Methods: Evaluation of anti-gastric ulcer activity of PPE was performed using three induced gastric ulcers models: (1) ethanol/hydrochloric acid (EtOH/HCl), (2) restraint water immersion stress and (3) indomethacin. Ulcer indices were determined by microscopic examination (10X). Pylorus ligation and gastric-wall mucus determination were used to investigate the mechanism of anti-gastric ulcer activity of PPE.Results: Oral administration of PPE (150, 300 and 600 mg/kg) significantly inhibited gastric ulcer formation induced by EtOH/HCl, by water immersion restraint stress, and by indomethacin in rats (p-value |
| Databáze: | Directory of Open Access Journals |
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