Autor: |
Chi Zhang, Maria B. Lai, Lavan Khandan, Lindsey A. Lee, Zhe Chen, Harald J. Junge |
Jazyk: |
angličtina |
Rok vydání: |
2017 |
Předmět: |
|
Zdroj: |
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017) |
Druh dokumentu: |
article |
ISSN: |
2041-1723 |
DOI: |
10.1038/ncomms16050 |
Popis: |
Multiple mechanisms regulate Wnt/ß-catenin signalling. Zhanget al. describe a novel regulatory pathway and show that the activator of canonical Wnt signalling, Norrin, triggers endocytosis of its receptor Frizzled4 by promoting Frizzled4 ubiquitination. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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