Primary Thyroid Lymphoma: A Rare Diagnosis Treated With Polatuzumab Vedotin

Autor: Rupam Sharma MD, Arin Orogian DO, Ralph Garcia-Pacheco MD, Tung Trang MD, Matthew Clarke MD, William Stull MD, Stanley Kim MD
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Journal of Investigative Medicine High Impact Case Reports, Vol 12 (2024)
Druh dokumentu: article
ISSN: 2324-7096
23247096
DOI: 10.1177/23247096241299566
Popis: Primary thyroid lymphoma is one of the rare and distinct type of extra nodal lymphomas originating within the thyroid gland. It accounts for less than 5% of all thyroid malignancies and 2% of extra nodal lymphomas. It predominantly affects older adults, with a higher incidence in women. Patients typically present with a rapidly enlarging thyroid mass, accompanied by clinical symptoms of compression such as dysphagia, dyspnea, and hoarseness. Diagnosis is established through a combination of fine-needle aspiration, core needle biopsy, and advanced imaging techniques. Standard treatment involves a multimodal strategy of chemotherapy, often with the addition of radiotherapy and surgical intervention. Herein presented is the first reported case of diffuse large B-cell lymphoma treated with Pola-R-CHP.
Databáze: Directory of Open Access Journals