Clinical Efficacy of Intravenous Papaverine plus Ketorolac in the Emergency Treatment of Renal Colic: A Randomized, Double-blind Clinical Trial
| Autor: | Javad Mozafari, Ali Khavanin, Ali Delirrooyfard, Mohammadreza Pirouzi, Naeimehossadat Asmarian |
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| Jazyk: | angličtina |
| Rok vydání: | 2024 |
| Předmět: | |
| Zdroj: | Iranian Journal of Medical Sciences, Vol 49, Iss 11, Pp 691-698 (2024) |
| Druh dokumentu: | article |
| ISSN: | 0253-0716 1735-3688 |
| DOI: | 10.30476/ijms.2023.100323.3251 |
| Popis: | Background: Acute renal colic has been challenging and has brought many concerns for physicians and patients for centuries. This study aimed to evaluate the analgesic effect and safety of a combination of papaverine and ketorolac against ketorolac and placebo in treating acute renal colic.Methods: This randomized clinical trial was performed in patients with renal colic from May 2018 to May 2020 in Ahvaz, Iran. Patients with colic pain due to sand or kidney stones underwent clinical examination. The pain intensified based on the visual analog scale (VAS) and the patients’ need for rescue analgesia are considered as primary outcomes at various times after treatment. Patients were equally divided into two groups: A (ketorolac plus papaverine) and B (ketorolac plus placebo) by block balanced randomization method. Student t test, the Chi square, and ANOVA tests were used for statistical analyses, which were performed by SPSS 19.0. P |
| Databáze: | Directory of Open Access Journals |
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