| Autor: |
Valeria Poloni, Alejandra Magnoli, Analía Fochesato, Andrea Cristofolini, Matías Caverzan, Cecilia Merkis, Mariana Montenegro, Lilia Cavaglieri |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
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| Zdroj: |
Animal Nutrition, Vol 6, Iss 1, Pp 31-38 (2020) |
| Druh dokumentu: |
article |
| ISSN: |
2405-6545 |
| DOI: |
10.1016/j.aninu.2019.11.006 |
| Popis: |
The present study was conducted to investigate the ability of Saccharomyces cerevisiae RC016 (Sc)-based feed additive to reduce liver toxicity, residual aflatoxin B1 (AFB1) levels and influence intestinal structure in broiler chickens fed chronic aflatoxin B1-contaminated diets. A total of 100 one-day-old male commercial line (Ross) broiler chickens were divided into 4 treatments, with 5 pens per treatment and 5 broiler chickens per pen. Birds were randomly assigned to 4 treatments, which were namely treatment 1 (T1), control diet (CD); T2, CD + Sc at 1 g/kg; T3, CD + AFB1 at 100 μg/kg; T4, CD + Sc at 1 g/kg + AFB1 at 100 μg/kg. The liver histopathology of broiler chickens fed diets with AFB1 showed diffused microvacuolar fatty degeneration. The addition of Sc showed normal hepatocytes similar to the control. The small intestine villi from AFB1 group showed atrophy, hyperplasia of goblet cells, prominent inflammatory infiltrate and oedema. In contrast, the small intestine villi from birds that received the yeast plus AFB1 showed an absence of inflammatory infiltrate, and atrophy; moreover, a lower number of goblet cells compared to the groups with AFB1 was observed. The morphometric intestine studies showed that a significant decrease (P 0.05), there was a tendency to improve these parameters. The residual levels of AFB1 in livers were significantly reduced (P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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