Proximal deep vein thrombosis among hospitalised medical and obstetric patients in Rwandan university teaching hospitals: prevalence and associated risk factors: a cross-sectional study

Autor: Timothy David Walker, Regine Mugeni, Eugene Nkusi, Eric Rutaganda, Sanctus Musafiri, Florence Masaisa, Kayan Lea Lewis, Marc Simpao, Pierrot Lundimu Tugirimana
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: BMJ Open, Vol 9, Iss 11 (2019)
Druh dokumentu: article
ISSN: 2044-6055
DOI: 10.1136/bmjopen-2019-032604
Popis: Objectives To determine the prevalence of proximal deep vein thrombosis (DVT) by ultrasound scanning, as well as associated clinical features and known risk factors, among medical and obstetrics–gynaecology inpatients in two Rwandan tertiary hospitals.Design Cross-sectional study.Settings Rwanda teaching hospitals: Kigali and Butare University Teaching Hospitals.Participants 901 adult patients admitted to the Departments of Internal Medicine and Obstetrics–Gynecology (O&G) who were at least 21 years of age and willing to provide a consent.Outcomes Prevalence of proximal DVT, clinical features and known risk factors associated with DVT.Methods Between August 2015 and August 2016, participants were screened for DVT by compressive ultrasound of femoral and popliteal veins, conducted as a monthly cross-sectional survey of all consenting eligible inpatients. Patients completed a self-report survey on DVT risk factors. Prevalence of proximal DVT by compression ultrasonography was the primary endpoint, with univariate and multivariate regression analyses performed to assess associated clinical features and risk factors.Results Proximal DVT was found in 5.5% of the study population, with similar rates in medical and O&G inpatients. The mean age was 41±16 SD (range, 21–91), 70% were female and 7% were pregnant. Univariate analysis showed active malignancy, immobilisation, prolonged recent travel and history of DVT to be significant risk factors for proximal DVT (all p values
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