T-regulatory cells subpopulation in bronchial asthma and heterogeneous phenotypes of chronic obstructive pulmonary disease
| Autor: | N. A. Kirillova, I. A. Deyev, Ye. E. Kremer, L. M. Ogorodova, G. E. Chernogoryuk |
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| Jazyk: | English<br />Russian |
| Rok vydání: | 2011 |
| Předmět: | |
| Zdroj: | Бюллетень сибирской медицины, Vol 10, Iss 1, Pp 48-54 (2011) |
| Druh dokumentu: | article |
| ISSN: | 1682-0363 1819-3684 |
| DOI: | 10.20538/1682-0363-2011-1-48-54 |
| Popis: | Aim of the study was to investigate the levels of individual subpopulations of T-regulatory (T-reg) cells in patients with different phenotypes of chronic obstructive pulmonary disease (COPD) with moderate bronchial asthma and healthy volunteers. COPD was associated with increased level of natural (CD4+CD25high) T-cells, while emphysematous phenotype of disease was associated with the highest pool of natural CD4+CD25high. Bronchial asthma was associated with low levels of inducible (CD4+ FoxP3+ ) T-reg. |
| Databáze: | Directory of Open Access Journals |
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